FOOD IS MEDICINE
UNLOCK THE SECRETS OF YOUR DNA
Medicine and Nutrition are in the process of a remarkable genetics technology. We now have the ability to identify DNA sequencing and the molecular code governing each unique characteristic of our metabolism. This translates into the ability to tests for over 75 genetic markers known to influence metabolism. The science gives us the ability to determine our tendencies for weight gain, obesity, and the predisposition to diseases. This revolutionary testing also enables us to test for how nutrients are absorbed. This translates into the ability to accurately design a regime to support weight loss, weight maintenance, and general well-being. This technology guides on how we should divide the percentage of carbohydrates, protein and fat, ultimately tailoring a meal plan.. We can optimize our nutritional status by genetic markers to determine if we should be eating a lower carbohydrate, lower fat diet, or a more balanced diet. We can also test for the type of fat that is optimal for our metabolism and fine tune the amount of saturated, unsaturated, or monounsaturated fat that is ideal for us.
THE GENETICS OF OBESITY
There is a lot of attention focused on the enlarging waistline. It is a nationwide concern since it is increasing and becoming an epidemic in the US as well as some other countries. Obesity is influenced by both genetic and environmental factors. Some propose that approximately 40 to 70% of an individual’s susceptibility to obesity is inherited. Your genetic predisposition to obesity is determined from your genotypes specifically at variants in the FTO(fat mass and obesity associated) and MC4R(melanocortin-4 receptor genes). We test for both of these since they are important in regulating hunger and energy balance.
Adiponetin is a hormone that is produced by fat cells. It functions in the body to trigger your liver and muscles to get energy from fat. Higher levels of adiponectin are considered good for weight loss and health. If you have low levels, losing weight may be a good way to increase levels. It is important to test for this gene, since a program of resistant exercises and a higher protein regime can help. Insulin is a hormone, necessary for the control of blood sugar. Insulin sensitivity is a desired effect that enables your body to process glucose and prevent diabetes. The opposite of insulin sensitivity is insulin resistance, which predisposes to obesity and type 2 diabetes Exercise is an integral part of general health as well as for weight maintenance. Certain genotypes respond better to exercise, specifically genotype C/C, and C/T in the LPL gene. If you possess other genotypes such as the T/T, it may take more effort to lose weight with exercise.
We use body mass index (BMI) as a scale to measure body fat based on height and weight. BMI is usually represented in kg/m2. Keep in mind that your actual weight is a result of a combination of factors including lifestyle, environment and genetics. The BMI scale is as follows:
Underweight less than 18.5
Obese 30 to 34.9
Clinically obese 35 to 39.9
Extremely Obese 40 or greater
Fats are an important part of any diet and a source of energy. Fat provides flavor, essential fatty acids, and is vital in the absorption of fat-soluble vitamins such as ADEK. The two major types of fat include: unsaturated (polyunsaturated and monounsaturated) and saturated fat. In order, for your body to function normally, you need to maintain a consistent and balanced supply. A third type of fats consists of hydrogenated fats and trans fatty acids, which are processed fats not found naturally. This includes margarines, baked foods, and fried fast foods. We test for two genes (ADIPOQ and PPARG) which determine the ratio of fatty acids that you will benefit most from. For example, there is a gene associated with lower body weight, when more than 13% of their calories come from monounsaturated fats.